Panic disorder and a possible treatment approach by means of high-frequency rTMS: a case report

World J Biol Psychiatry. 2009;10(4 Pt 3):991-7. doi: 10.1080/15622970902898147.

Abstract

Panic disorder still remains a pervasive, life quality impairing disorder requiring adequate treatment options. In this case report we present the data of a patient with panic disorder and comorbid depression who was treated with high-frequency repetitive transcranial magnetic stimulation (rTMS) applied to the left prefrontal cortex over a course of 3 weeks. Measurements of the cerebral oxygenation with near-infrared spectroscopy (NIRS) during an emotional Stroop task before and after the rTMS treatment suggests that rTMS may modulate panic-related prefrontal brain dysfunctions in panic patients and that it may serve as a possible treatment option for anxiety disorders.

Publication types

  • Case Reports
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adrenergic Uptake Inhibitors / therapeutic use
  • Adrenergic alpha-Antagonists / therapeutic use
  • Adrenergic beta-Antagonists / therapeutic use
  • Adult
  • Amitriptyline / therapeutic use
  • Bisoprolol / therapeutic use
  • Combined Modality Therapy
  • Drug Therapy, Combination
  • GABA Modulators / therapeutic use
  • Humans
  • Male
  • Panic Disorder / drug therapy
  • Panic Disorder / therapy*
  • Sulfonamides / therapeutic use
  • Tamsulosin
  • Temazepam / therapeutic use
  • Transcranial Magnetic Stimulation / methods*

Substances

  • Adrenergic Uptake Inhibitors
  • Adrenergic alpha-Antagonists
  • Adrenergic beta-Antagonists
  • GABA Modulators
  • Sulfonamides
  • Amitriptyline
  • Temazepam
  • Tamsulosin
  • Bisoprolol