Immunological's host profile for HPV and Chlamydia trachomatis, a cervical cancer cofactor

Ana Catarina Simonetti; José Humberto de Lima Melo; Paulo Roberto Eleutério de Souza; Danyelly Bruneska; José Luiz de Lima Filho

doi:10.1016/j.micinf.2009.01.004

Immunological's host profile for HPV and Chlamydia trachomatis, a cervical cancer cofactor

Microbes Infect. 2009 Apr;11(4):435-42. doi: 10.1016/j.micinf.2009.01.004.

Authors

Ana Catarina Simonetti¹, José Humberto de Lima Melo, Paulo Roberto Eleutério de Souza, Danyelly Bruneska, José Luiz de Lima Filho

Affiliation

¹ Laboratory of Immunopathology Keizo Asami, Federal University of Pernambuco, Av. Professor Moraes Rego, Campus Universitário s/n, Recife, PE, Brazil.

PMID: 19397882
DOI: 10.1016/j.micinf.2009.01.004

Abstract

Over 100 different genotypes of human papillomavirus (HPV) have been isolated to date, while Chlamydia trachomatis is the most common bacterial sexually-transmitted pathogen. This review considers evidence that C. trachomatis infection became a cofactor for HPV establishment and the development of cervical intraepithelial neoplasia.

Publication types

Review

MeSH terms

Chlamydia Infections / complications*
Chlamydia Infections / immunology
Chlamydia trachomatis / immunology*
Female
Humans
Papillomaviridae / immunology*
Papillomavirus Infections / complications*
Papillomavirus Infections / immunology
Uterine Cervical Neoplasms / microbiology*
Uterine Cervical Neoplasms / virology*