Discovery and optimization of a TRAIL R2 agonist for cancer therapy

Adv Exp Med Biol. 2009:611:101-3. doi: 10.1007/978-0-387-73657-0_45.

Authors

Yvonne M Angell¹, Ashok Bhandari, M Nuria De Francisco, Brian T Frederick, Jennifer M Green, Karen Leu, Kerstin Leuther, Reuben Sana, Peter J Schatz, Erik A Whitehorn, Kathy Wright, Christopher P Holmes

Affiliation

¹ Affymax, Inc., 4001 Miranda Avenue, Palo Alto, CA 94304, USA.

PMID: 19400112
DOI: 10.1007/978-0-387-73657-0_45

No abstract available

MeSH terms

Amino Acid Sequence
Chromatography, High Pressure Liquid
Drug Discovery*
Humans
Mass Spectrometry
Molecular Mimicry
Molecular Sequence Data
Neoplasms / drug therapy*
Receptors, TNF-Related Apoptosis-Inducing Ligand / agonists*

Substances

Receptors, TNF-Related Apoptosis-Inducing Ligand