Discovery of a ligand that compensates for decreased endogenous agonist potency of melanocortin-4 receptor polymorphisms identified in obese humans

Adv Exp Med Biol. 2009:611:509-10. doi: 10.1007/978-0-387-73657-0_221.

Authors

Carrie Haskell-Luevano¹, Zhimin Xiang, Andrzej M Wilczynski, Kimberly R Haskell, Amy M Andreasen, Sally A Litherland, William J Millard, Ira D Pogozheva, Henry I Mosberg, Nicholas B Sorenson

Affiliation

¹ Department of Medicinal Chemistry, University of Florida, Gainesville, FL 32610, USA.

PMID: 19400288
DOI: 10.1007/978-0-387-73657-0_221

No abstract available

Publication types

Research Support, N.I.H., Extramural
Research Support, Non-U.S. Gov't

MeSH terms

Humans
Ligands
Obesity / genetics*
Polymorphism, Genetic*
Receptor, Melanocortin, Type 4 / agonists*
Receptor, Melanocortin, Type 4 / genetics

Substances

Ligands
Receptor, Melanocortin, Type 4

Grants and funding