Abstract
The parallel kinetic resolution of racemic 2-aryl-2-deuterio-propionic and butanoic acids using an equimolar combination of quasi-enantiomeric oxazolidin-2-ones is discussed. The levels of diastereoselectivity were high leading to enantiomerically pure D-labeled products in good yield.
2009 Wiley-Liss, Inc.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Animals
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Antifungal Agents / chemistry
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Biocatalysis*
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Butyrates / chemistry*
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Chromatography, High Pressure Liquid
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Crystallography, X-Ray
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Equipment Design
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Female
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Flow Injection Analysis
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Hydrogen-Ion Concentration
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Kinetics
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Lactation / metabolism*
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Larva / drug effects
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Microbial Sensitivity Tests
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Models, Molecular
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Molecular Structure
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Oxadiazoles / chemistry*
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Oxazolidinones / chemical synthesis*
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Oxazolidinones / chemistry
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Propionates / chemistry*
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Stereoisomerism*
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Structure-Activity Relationship
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Sweetening Agents / chemistry
Substances
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Antifungal Agents
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Butyrates
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Oxadiazoles
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Oxazolidinones
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Propionates
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Sweetening Agents