Surfactant therapy in acute respiratory distress syndrome due to hydrocarbon aspiration

Singapore Med J. 2009 Apr;50(4):e130-2.

Abstract

Hydrocarbon aspiration causes acute lung injury, which may lead to acute respiratory distress syndrome. Surfactant has been shown to be beneficial in experimentally-induced hydrocarbon-associated acute respiratory distress syndrome. However, there has not been a clinical study evaluating the effect of surfactant application on hydrocarbon aspiration in humans. We report a 17-month-old boy with acute respiratory distress syndrome due to hydrocarbon aspiration and was successfully treated with surfactant application.

Publication types

  • Case Reports

MeSH terms

  • Alkanes / poisoning*
  • Anti-Infective Agents / administration & dosage
  • Biological Products / administration & dosage*
  • Ceftriaxone / administration & dosage
  • Combined Modality Therapy
  • Critical Care
  • Dopamine / administration & dosage
  • Humans
  • Hydrocarbons / poisoning*
  • Infant
  • Male
  • Positive-Pressure Respiration
  • Pulmonary Surfactants / administration & dosage*
  • Radiography
  • Respiratory Aspiration / complications*
  • Respiratory Aspiration / diagnostic imaging
  • Respiratory Distress Syndrome / chemically induced*
  • Respiratory Distress Syndrome / diagnostic imaging
  • Respiratory Distress Syndrome / drug therapy*
  • Trachea
  • Turkey

Substances

  • Alkanes
  • Anti-Infective Agents
  • Biological Products
  • Hydrocarbons
  • Pulmonary Surfactants
  • Ceftriaxone
  • naphtha
  • beractant
  • Dopamine