Abstract
Reports an efficient chemoenzymatic production of an N-acetylhexosamine 1-phophate analogues library by N-acetylhexosamine 1-kinase (NahK) and describes the respective substrate specificity on this enzyme.
Publication types
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Research Support, N.I.H., Extramural
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Research Support, Non-U.S. Gov't
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Research Support, U.S. Gov't, Non-P.H.S.
MeSH terms
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Acetylglucosamine / analogs & derivatives*
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Acetylglucosamine / chemical synthesis
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Acetylglucosamine / chemistry
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Acetylglucosamine / metabolism
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Adenosine Triphosphate / chemical synthesis
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Adenosine Triphosphate / metabolism
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Bifidobacterium / enzymology*
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Isomerism
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Phosphotransferases / chemical synthesis
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Phosphotransferases / metabolism*
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Small Molecule Libraries / chemical synthesis*
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Small Molecule Libraries / chemistry
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Small Molecule Libraries / metabolism*
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Substrate Specificity
Substances
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Small Molecule Libraries
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N-acetylglucosamine-1-phosphate
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Adenosine Triphosphate
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Phosphotransferases
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Acetylglucosamine