Construction of nitrogen-containing heterocycles by C-H bond functionalization

Chemistry. 2009 Jun 8;15(24):5874-83. doi: 10.1002/chem.200900281.

Abstract

Nitrogen heterocycles are abundant in natural products and pharmaceuticals. An emerging interest among synthetic chemists is to use C-H functionalization to construct the nitrogen-containing core of these heterocycles. The following article will provide a brief overview of this concept with respect to the type of C-H bond functionalized.

MeSH terms

  • Heterocyclic Compounds / chemical synthesis*
  • Heterocyclic Compounds / chemistry
  • Hydrogen Bonding*
  • Molecular Structure
  • Nitrogen / chemistry*

Substances

  • Heterocyclic Compounds
  • Nitrogen