Dual-rhodamine urea derivative, a novel chemidosimeter for Hg(II) and its application in imaging Hg(II) in living cells

Pin-xian Xi; Liang Huang; Heng Liu; Peng-fei Jia; Feng-juan Chen; Min Xu; Zheng-zhi Zeng

doi:10.1007/s00775-009-0546-0

Dual-rhodamine urea derivative, a novel chemidosimeter for Hg(II) and its application in imaging Hg(II) in living cells

J Biol Inorg Chem. 2009 Aug;14(6):815-9. doi: 10.1007/s00775-009-0546-0. Epub 2009 May 15.

Authors

Pin-xian Xi¹, Liang Huang, Heng Liu, Peng-fei Jia, Feng-juan Chen, Min Xu, Zheng-zhi Zeng

Affiliation

¹ State Key Laboratory of Applied Organic Chemistry, College of Chemistry and Chemical Engineering, Lanzhou University, Lanzhou, People's Republic of China.

PMID: 19444491
DOI: 10.1007/s00775-009-0546-0

Abstract

The synthesis and spectral properties of a chemidosimeter 1,4-di[2-(6-ethylamino-3-ethylimino-2,7-dimethyl-3H-xanthen-9-yl) benzoic acid (aminomethyl)-3-phenylthiourea] benzene (1) for Hg(II) ions are reported, and it has been demonstrated that 1 can be used as a fluorescent probe for monitoring Hg(II) ions in living cells.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Cell Survival
Cells / chemistry*
Cells / cytology*
Environmental Pollutants / analysis*
Fluorescent Dyes / chemistry*
HeLa Cells
Humans
Hydrogen-Ion Concentration
Mercury / analysis*
Rhodamines / chemistry*
Spectrometry, Fluorescence
Spectrophotometry, Ultraviolet
Temperature
Urea / analogs & derivatives*
Urea / chemistry

Substances

1,4-di(2-(6-ethylamino-3-ethylimino-2,7-dimethyl-3H-xanthen-9-yl)benzoic acid (aminomethyl)-3-phenylthiourea)benzene
Environmental Pollutants
Fluorescent Dyes
Rhodamines
Urea
Mercury