[Studies on triterpenoid saponins in Hemsleya chensnsis]

Zhongguo Zhong Yao Za Zhi. 2009 Feb;34(3):291-3.
[Article in Chinese]

Abstract

Objective: To study the triterpenoid saponins in Hemsleya chensnsis.

Method: The chemical constituents were isolated and purified by various chromatographic methods and their structures were elucidated on the basis of spectral analysis.

Result: Seven known triterpenoid saponins were isolated from the root of H. chensnsis and were identified as 3-O-beta-D-glucuropyranosyl-oleanol-icacid (1), 3-O-beta-D-glucopyra-noside-oleanolicacid-28-O-beta-D-glucopyranoside (2), 3-O-(6'-methylester)-beta-D-glucuropyranosyl olea- nolic acid-28-O-alpha-L-arabinopyranoside (3), 3-O-(6'-methylester)-beta-D- glucuropyranosyl- oleanolic acid-28-O-beta-D-mannupyranoside (4), 3-O-(6'-ethyl ester)-beta-D-glucuropyranosyl oleanolic acid-28-O-beta-D- glucopyranoside (5), 3-O-alpha-L-arabinopyranoside-(1-->3) -beta-D-glucuropyranosyl- oleanolic acid-28-O-beta-D-glucopyranoside (6), 3-O-beta-D-glucu-ropyranosyl-oleanolic acid-28-O-beta-D-glucopyra-noside-(1-->6)-beta-D-glucopyranoside (7).

Conclusion: Compounds 1-7 were isolated from this plant for the first time.

Publication types

  • English Abstract

MeSH terms

  • Cucurbitaceae / chemistry
  • Drugs, Chinese Herbal / pharmacology
  • Mitragyna / chemistry
  • Molecular Structure
  • Plant Extracts / pharmacology*
  • Plant Roots / chemistry*
  • Saponins / chemistry*
  • Saponins / isolation & purification

Substances

  • Drugs, Chinese Herbal
  • Plant Extracts
  • Saponins