Rapid selection and archiving of mutation E157Q in HIV-1 DNA during short-term low-level replication on a raltegravir-containing regimen

J Antimicrob Chemother. 2009 Aug;64(2):433-4. doi: 10.1093/jac/dkp182. Epub 2009 May 20.
No abstract available

Publication types

  • Case Reports
  • Letter

MeSH terms

  • Amino Acid Substitution / genetics
  • Anti-HIV Agents / therapeutic use*
  • Antiretroviral Therapy, Highly Active
  • Drug Resistance, Viral*
  • HIV Infections / drug therapy*
  • HIV Infections / virology
  • HIV Integrase / genetics
  • HIV-1 / drug effects*
  • HIV-1 / isolation & purification
  • Humans
  • Male
  • Mutation, Missense*
  • Pyrrolidinones / therapeutic use*
  • Raltegravir Potassium
  • Selection, Genetic*

Substances

  • Anti-HIV Agents
  • Pyrrolidinones
  • Raltegravir Potassium
  • HIV Integrase
  • p31 integrase protein, Human immunodeficiency virus 1