Efficacy of moxidectin against cyathostomins after long-term use in a large herd of draught horses with a high stocking density

J Schumacher; L Livesey; F DeGraves; B Blagburn; S Ziska; M Caldwell; K Brock

doi:10.1136/vr.164.21.652

Efficacy of moxidectin against cyathostomins after long-term use in a large herd of draught horses with a high stocking density

Vet Rec. 2009 May 23;164(21):652-4. doi: 10.1136/vr.164.21.652.

Authors

J Schumacher¹, L Livesey, F DeGraves, B Blagburn, S Ziska, M Caldwell, K Brock

Affiliation

¹ Department of Clinical Sciences, College of Veterinary Medicine, Auburn University, Auburn, AL 36849, USA.

PMID: 19465754
DOI: 10.1136/vr.164.21.652

Abstract

This study was undertaken to determine whether resistance to moxidectin had developed in a large herd of draught horses, maintained on a small acreage, which had been routinely treated with moxidectin for five years. Faeces were collected for egg counts immediately before moxidectin gel was administered orally, and seven, 30, 60 and 90 days later. The faecal egg counts were significantly reduced at seven and 30 days after treatment, but were not significantly different from pretreatment counts at 60 and 90 days after treatment. There was no evidence of resistance having developed.

Publication types

Evaluation Study

MeSH terms

Alabama
Analysis of Variance
Animal Husbandry
Animals
Antinematodal Agents / pharmacology*
Antinematodal Agents / standards
Drug Resistance
Drug Therapy, Combination
Feces / parasitology
Gels
Horse Diseases / drug therapy*
Horse Diseases / parasitology
Horses
Macrolides / pharmacology
Macrolides / standards
Parasite Egg Count / veterinary
Praziquantel / pharmacology
Praziquantel / standards
Strongylida Infections / drug therapy
Strongylida Infections / parasitology
Strongylida Infections / veterinary*
Strongyloidea / drug effects*
Time Factors
Treatment Outcome

Substances

Antinematodal Agents
Gels
Macrolides
Praziquantel
moxidectin