Acute pancreatitis as the initial presentation in pediatric systemic lupus erythematosus

Indian J Pediatr. 2009 Aug;76(8):846-7. doi: 10.1007/s12098-009-0156-4. Epub 2009 May 27.

Abstract

It is exceptionally rare for acute pancreatitis to be the presenting manifestation of childhood systemic lupus erythematosus. We report a 14-year-old girl who presented with a history of fever, generalized rash, arthralgia and abdominal pain. Her serum amylase was 1472U/L and lipase 3316 U/L suggestive of acute pancreatitis. Other investigations revealed pancytopenia, low complement, high 24-hour urinary protein and elevated ANA and dsDNA. She was treated with IV methylprednisone, followed by oral steroids.

Publication types

  • Case Reports

MeSH terms

  • Acute Disease
  • Administration, Oral
  • Adolescent
  • Diagnosis, Differential
  • Fatal Outcome
  • Female
  • Glucocorticoids / administration & dosage
  • Glucocorticoids / therapeutic use
  • Humans
  • Infusions, Intravenous
  • Lupus Erythematosus, Systemic / complications*
  • Lupus Erythematosus, Systemic / diagnosis
  • Lupus Erythematosus, Systemic / drug therapy
  • Methylprednisolone / administration & dosage
  • Methylprednisolone / therapeutic use
  • Pancreatitis / diagnosis
  • Pancreatitis / drug therapy
  • Pancreatitis / etiology*

Substances

  • Glucocorticoids
  • Methylprednisolone