First isolation of Burkholderia tropica from a neonatal patient successfully treated with imipenem

Int J Infect Dis. 2010 Jan;14(1):e73-4. doi: 10.1016/j.ijid.2009.03.005. Epub 2009 May 23.

Abstract

We report the first case of a human Burkholderia tropica infection. The patient was a premature neonate who had necrotizing enterocolitis with bowel perforation requiring surgical intervention. The stoma care and difficulties in feeding were a chronic problem. At the age of almost 4 months he developed septicemia due to B. tropica. Three consecutive blood cultures grew this organism. The organism was cleared from the blood after a course of imipenem and resolution of post-operative ileus. Our case suggests that environmental and plant pathogens can cause human infection especially in those in an immunocompromised condition.

Publication types

  • Case Reports

MeSH terms

  • Anti-Bacterial Agents / therapeutic use*
  • Bacteremia / diagnosis*
  • Bacteremia / drug therapy
  • Bacteremia / microbiology
  • Burkholderia / classification
  • Burkholderia / genetics
  • Burkholderia / isolation & purification*
  • Burkholderia Infections / diagnosis*
  • Burkholderia Infections / drug therapy
  • Burkholderia Infections / microbiology
  • Fatal Outcome
  • Humans
  • Imipenem / therapeutic use*
  • Immunocompromised Host
  • Infant, Newborn
  • Infant, Premature
  • Male
  • Risk Factors

Substances

  • Anti-Bacterial Agents
  • Imipenem