Human parechovirus-3 infection: emerging pathogen in neonatal sepsis

Pediatr Infect Dis J. 2009 Jun;28(6):545-7. doi: 10.1097/INF.0b013e318194596a.

Abstract

Human parechovirus-3 (HPeV-3) is an emerging pathogen that has been described as a cause of neonatal sepsis. Human parechoviruses are a family of viruses closely related to enteroviruses; however, enteroviral PCR will not detect HPeVs. We present clinical details of neonatal meningoencephalitis and hepatitis-coagulopathy syndrome caused by HPeV-3 infection.

Publication types

  • Case Reports

MeSH terms

  • Acyclovir / therapeutic use
  • Antiviral Agents / therapeutic use
  • Cerebrospinal Fluid / virology
  • Humans
  • Infant, Newborn
  • Male
  • Meningoencephalitis / diagnosis*
  • Meningoencephalitis / drug therapy
  • Meningoencephalitis / virology
  • Parechovirus / genetics
  • Parechovirus / isolation & purification*
  • Parechovirus / pathogenicity
  • Picornaviridae Infections / diagnosis*
  • Picornaviridae Infections / drug therapy
  • Picornaviridae Infections / virology
  • Polymerase Chain Reaction
  • Sepsis / diagnosis*
  • Sepsis / drug therapy
  • Sepsis / virology

Substances

  • Antiviral Agents
  • Acyclovir