Abstract
We report on a case of diffuse alveolar haemorrhage in a Chinese woman due to methimazole-induced antineutrophil cytoplasmic antibodies. A literature search for anti-thyroid drugs associated with antineutrophil cytoplasmic antibody-induced diffuse alveolar haemorrhages is reviewed. Diffuse alveolar haemorrhage is a rare complication of thiourea agents and the treatment often requires corticosteroids or other immunosuppressants, together with withdrawal of the causative agent.
MeSH terms
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Adult
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Antibodies, Antineutrophil Cytoplasmic / blood*
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Antithyroid Agents / adverse effects*
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Antithyroid Agents / therapeutic use
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Comorbidity
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Female
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Graves Disease / drug therapy*
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Graves Disease / epidemiology
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Hemorrhage / epidemiology
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Hemorrhage / immunology*
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Humans
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Lung Diseases / epidemiology
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Lung Diseases / immunology*
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Methimazole / adverse effects*
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Methimazole / therapeutic use
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Pulmonary Alveoli*
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Vasculitis / immunology
Substances
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Antibodies, Antineutrophil Cytoplasmic
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Antithyroid Agents
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Methimazole