Mutiniside, new antioxidant phenolic glucoside from Abutilon muticum

J Asian Nat Prod Res. 2009;11(5):457-64. doi: 10.1080/10286020902835539.

Abstract

Mutiniside (1), new phenolic glucoside, and the flavonoidal glucoside cephacoside (2) have been isolated from the n-BuOH soluble fraction, along with lupeol (3), beta-sitosterol (4), stigmasterol (5), methyl-4-hydroxybenzoate (6), taraxacin (7), ursolic acid (8), and beta-sitosterol-3-O-beta-D-glucopyranoside (9), have been isolated from the EtOAc soluble fraction of Abutilon muticum. Compounds 2-9 are reported for the first time from this species. Compound 1 showed significant antioxidant activity while moderate inhibitory activity was observed against the enzyme lipoxygenase.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Antioxidants / chemistry
  • Antioxidants / isolation & purification*
  • Antioxidants / pharmacology*
  • Biphenyl Compounds / pharmacology
  • Free Radical Scavengers / pharmacology
  • Glucosides / chemistry
  • Glucosides / isolation & purification*
  • Glucosides / pharmacology*
  • Lipoxygenase Inhibitors / chemistry
  • Lipoxygenase Inhibitors / isolation & purification*
  • Lipoxygenase Inhibitors / pharmacology*
  • Malvaceae / chemistry*
  • Molecular Structure
  • Pakistan
  • Phenols / chemistry
  • Phenols / isolation & purification
  • Phenols / pharmacology
  • Picrates / pharmacology
  • Plants, Medicinal / chemistry*
  • Sitosterols / chemistry
  • Sitosterols / isolation & purification

Substances

  • Antioxidants
  • Biphenyl Compounds
  • Free Radical Scavengers
  • Glucosides
  • Lipoxygenase Inhibitors
  • Phenols
  • Picrates
  • Sitosterols
  • mutiniside
  • sitosterol-3-O-glucopyranoside
  • gamma-sitosterol
  • 1,1-diphenyl-2-picrylhydrazyl