New families of enantiopure cyclohexenone cis-diol, o-quinol dimer and hydrate metabolites from dioxygenase-catalysed dihydroxylation of phenols

Chem Commun (Camb). 2009 Jun 28:(24):3633-5. doi: 10.1039/b905940g. Epub 2009 May 13.

Abstract

Toluene dioxygenase-catalysed cis-dihydroxylation of phenols has led to the discovery of new enantiopure cyclohexenone cis-diol, o-quinol dimer and phenol hydrate metabolites having synthetic potential.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Biocatalysis*
  • Crystallography, X-Ray
  • Cyclohexanones / chemical synthesis*
  • Cyclohexanones / chemistry
  • Dimerization
  • Dioxygenases / metabolism*
  • Hydroquinones / chemistry*
  • Models, Molecular
  • Molecular Structure
  • Phenols / chemistry*
  • Phenols / metabolism*
  • Stereoisomerism
  • Water / chemistry*

Substances

  • Cyclohexanones
  • Hydroquinones
  • Phenols
  • Water
  • cyclohexanone
  • Dioxygenases