Abstract
We investigated whether Merkel cell carcinoma (MCC) patients in France carry Merkel cell polyomavirus (MCPyV) and then identified strain variations. All frozen MCC specimens and 45% of formalin-fixed and paraffin-embedded specimens, but none of the non-MCC neuroendocrine carcinomas specimens, had MCPyV. Strains from France and the United States were similar.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Aged
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Aged, 80 and over
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Capsid Proteins / genetics
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Carcinoma, Merkel Cell / virology*
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DNA, Viral / analysis
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Female
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France / epidemiology
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Humans
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Male
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Merkel Cells / virology*
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Middle Aged
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Molecular Sequence Data
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Polymerase Chain Reaction / methods
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Polyomavirus Infections / virology*
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Polyomavirus* / classification
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Polyomavirus* / genetics
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Polyomavirus* / isolation & purification
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Sequence Analysis, DNA
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Skin Neoplasms / virology*
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Tumor Virus Infections / virology*
Substances
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Capsid Proteins
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DNA, Viral
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VP1 protein, polyomavirus
Associated data
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GENBANK/FM864207
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GENBANK/FM864208
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GENBANK/FM864209
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GENBANK/FM864210
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GENBANK/FM864211
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GENBANK/FM864212
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GENBANK/FM865403
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GENBANK/FM865404
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GENBANK/FM865405
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GENBANK/FM995488
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GENBANK/FM995489
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GENBANK/FM995490
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GENBANK/FM995609