Autogenous iliac crest bone graft versus banked allograft bone in scoliosis surgery in patients with Duchenne muscular dystrophy

Int Orthop. 2010 Aug;34(6):855-61. doi: 10.1007/s00264-009-0828-8. Epub 2009 Jun 16.

Abstract

A total of 36 consecutive nonambulatory DMD patients underwent scoliosis surgery. Patients were divided into two groups: the autogenous iliac crest bone graft group (the ICBG group; 20 patients) and the allogenous bone graft group (the ALBG group; 16 patients). The mean preoperative curves measured 87 degrees and 31 degrees at the last follow-up in the ICBG group and 83 degrees and 28 degrees in the ALBG group. In the ICBG group, three (15%) patients had intraoperative sacroiliac joint penetration, five (25%) had iliac crest inner cortex penetration and three (15%) had postoperative prolonged wound drainage at the donor site. At three months after surgery, donor site pain caused by bone harvest was found in 50% with severe pain limiting their physical function and causing difficulties in sitting in a wheelchair in 40% of the patients, whereas patients in the ALBG group returned to their preoperative level of function soon after surgery.

Publication types

  • Comparative Study

MeSH terms

  • Adolescent
  • Bone Transplantation / methods*
  • Child
  • Female
  • Follow-Up Studies
  • Humans
  • Ilium / surgery*
  • Male
  • Muscular Dystrophy, Duchenne / complications*
  • Muscular Dystrophy, Duchenne / surgery
  • Pain, Postoperative / etiology
  • Prospective Studies
  • Recovery of Function*
  • Scoliosis / etiology
  • Scoliosis / surgery*
  • Spinal Fusion / methods
  • Transplantation, Autologous / adverse effects
  • Transplantation, Homologous
  • Young Adult