Abstract
The adverse effects of regimes in cancer treatment have forced us to change to new targeted therapy options. Understanding these side effects, which can lead to discontinuation of the new therapy strategies, will allow the clinical management of these side effects and result in continuing therapies with effective medications. Bevacizumab, which is an IgG1 antibody against vascular endothelial growth factor, has side effects such as proteinuria, hypertension, venous and arterial thromboembolic events, and hemorrhage. This is the first reported case of dural sinus vein thrombosis, during the treatment with bevacizumab.
MeSH terms
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Antibodies, Monoclonal / therapeutic use*
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Antibodies, Monoclonal, Humanized
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Antineoplastic Combined Chemotherapy Protocols / adverse effects*
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Antineoplastic Combined Chemotherapy Protocols / therapeutic use
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Bevacizumab
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Camptothecin / adverse effects
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Camptothecin / analogs & derivatives
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Camptothecin / therapeutic use
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Colonic Neoplasms / complications
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Colonic Neoplasms / drug therapy*
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Fluorouracil / adverse effects
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Fluorouracil / therapeutic use
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Humans
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Leucovorin / adverse effects
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Leucovorin / therapeutic use
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Male
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Middle Aged
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Sinus Thrombosis, Intracranial / chemically induced*
Substances
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Antibodies, Monoclonal
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Antibodies, Monoclonal, Humanized
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Bevacizumab
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Leucovorin
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Fluorouracil
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Camptothecin