Palladium-catalyzed acylation of sp2 C-H bond: direct access to ketones from aldehydes

Xiaofei Jia; Shouhui Zhang; Wenhui Wang; Fang Luo; Jiang Cheng

doi:10.1021/ol900934g

Palladium-catalyzed acylation of sp2 C-H bond: direct access to ketones from aldehydes

Org Lett. 2009 Jul 16;11(14):3120-3. doi: 10.1021/ol900934g.

Authors

Xiaofei Jia¹, Shouhui Zhang, Wenhui Wang, Fang Luo, Jiang Cheng

Affiliation

¹ College of Chemistry & Materials Engineering, Wenzhou University, Wenzhou 325027, PR China.

PMID: 19552400
DOI: 10.1021/ol900934g

Abstract

A palladium-catalyzed direct access to ketones from aldehydes via C-H cleavage of arenes is described. The procedure utilizes air as a clean and free terminal oxidant.