Cyclization of hydrazones of 2-acetyl-1-naphthol and 1-acetyl-2-naphthol with triphosgene. Synthesis of Spiro naphthoxazine dimers

Abdullah Saad Al-Bogami; Abdullah Mohammed Al-Majid; Mohammed Ali Al-Saad; Ahmed Amine Mousa; Sara Abdullah Al-Mazroa; Hamad Zaid Alkhathlan

doi:10.3390/molecules14062147

Cyclization of hydrazones of 2-acetyl-1-naphthol and 1-acetyl-2-naphthol with triphosgene. Synthesis of Spiro naphthoxazine dimers

Molecules. 2009 Jun 12;14(6):2147-59. doi: 10.3390/molecules14062147.

Authors

Abdullah Saad Al-Bogami¹, Abdullah Mohammed Al-Majid, Mohammed Ali Al-Saad, Ahmed Amine Mousa, Sara Abdullah Al-Mazroa, Hamad Zaid Alkhathlan

Affiliation

¹ Department of Chemistry, King Saud University, P. O. Box 2455, Riyadh 11451, Saudi Arabia.

Abstract

Cyclization of hydrazones derived from 2-acetyl-1-naphthol and 1-acetyl-2-naphthol with triphosgene gave naphtho[1,2-e]-1,3-oxazines, naphtho[2,1-e]-1,3-oxazines or their spiro dimers depending on the molar ratio of triphosgene used for the cyclization.

MeSH terms

Cyclization
Hydrazones / chemical synthesis*
Hydrazones / chemistry*
Molecular Structure
Naphthols / chemistry*
Phosgene / analogs & derivatives*
Phosgene / chemistry

Substances

Hydrazones
Naphthols
Phosgene
1-naphthol
bis(trichloromethyl) carbonate
2-naphthol