The EmBlocker: efficiency of a new ultrasonic embolic protection device adjunctive to heart valve surgery

Ann Thorac Surg. 2009 Jul;88(1):253-7. doi: 10.1016/j.athoracsur.2009.01.058.

Abstract

Purpose: Perioperative cerebral microemboli in cardiac surgery are associated with postoperative neurologic complications. The EmBlocker (Neurosonix Ltd, Rehovot, Israel), a newly developed device should be positioned against the ascending aorta, and it produces an ultrasonic force expected to divert microemboli away from the cerebral vasculature and reduce cerebral emboli.

Description: Twenty-one consecutive patients, undergoing a valve procedure, were enrolled into this nonrandomized pilot study. The EmBlocker (Neurosonix Ltd) was positioned in 11 consecutive patients and activated for 1 minute (1.5 W/cm(2)) during seven selected aortic manipulations and for 10 minutes (0.5 W/cm(2)) intermittently after cross-clamp removal. Transcranial Doppler-based quantification of microembolic signals was performed in all patients.

Evaluation: The use of the EmBlocker showed a significant overall reduction of the cerebral microembolic signals of 53%.

Conclusions: The use of the EmBlocker during valve surgeries is associated with a reduction of perioperative cerebral microembolic signals. This new technology holds the potential to lower the risk of postoperative neurologic complications.

Publication types

  • Controlled Clinical Trial

MeSH terms

  • Aged
  • Aorta
  • Aortic Valve / surgery*
  • Equipment Design
  • Equipment Safety
  • Female
  • Follow-Up Studies
  • Heart Valve Diseases / diagnostic imaging
  • Heart Valve Diseases / surgery*
  • Heart Valve Prosthesis Implantation / adverse effects*
  • Heart Valve Prosthesis Implantation / methods
  • Humans
  • Intracranial Embolism / diagnostic imaging
  • Intracranial Embolism / prevention & control*
  • Male
  • Middle Aged
  • Monitoring, Intraoperative / instrumentation*
  • Monitoring, Intraoperative / methods
  • Pilot Projects
  • Probability
  • Reference Values
  • Risk Assessment
  • Sensitivity and Specificity
  • Transducers
  • Treatment Outcome
  • Ultrasonography, Doppler, Transcranial