Re: CDKL5 mutations in boys with severe encephalopathy and early-onset intractable epilepsy

Neurology. 2009 Jul 7;73(1):77-8; author reply 78. doi: 10.1212/01.wnl.0000349658.05677.d7.
No abstract available

Publication types

  • Case Reports
  • Letter
  • Research Support, Non-U.S. Gov't
  • Comment

MeSH terms

  • Age of Onset
  • Amino Acid Substitution / genetics
  • Brain Diseases, Metabolic / enzymology*
  • Brain Diseases, Metabolic / genetics*
  • Brain Diseases, Metabolic / physiopathology
  • Cerebral Cortex / pathology
  • Cerebral Cortex / physiopathology
  • Child, Preschool
  • Cohort Studies
  • DNA Mutational Analysis
  • Developmental Disabilities / enzymology
  • Developmental Disabilities / genetics
  • Developmental Disabilities / physiopathology
  • Disease Progression
  • Epilepsy / enzymology*
  • Epilepsy / genetics*
  • Epilepsy / physiopathology
  • Female
  • Genetic Markers / genetics
  • Genetic Predisposition to Disease / genetics*
  • Genetic Testing
  • Genotype
  • Humans
  • Male
  • Movement Disorders / enzymology
  • Movement Disorders / genetics
  • Movement Disorders / physiopathology
  • Muscle Hypotonia / etiology
  • Muscle Hypotonia / physiopathology
  • Mutation / genetics
  • Polymorphism, Single Nucleotide / genetics
  • Protein Serine-Threonine Kinases / genetics*

Substances

  • Genetic Markers
  • Protein Serine-Threonine Kinases
  • CDKL5 protein, human