[Successful cyclosporin therapy of acquired hemophilia caused by factor VIII (VIII:C) inhibiting antibody]

Orv Hetil. 1991 Jul 7;132(27):1485-8.
[Article in Hungarian]

Abstract

A 47-year-old woman is reported who had a life-threatening, subarachnoideal bleeding due to the spontaneous development of factor VIII:C inhibitor. Cyclosporin combined with prednisone allowed a full recovery and the elimination of antibody even when other therapeutic facilities failed to be effective. Actual problems of treatment of factor VIII inhibitors are briefly surveyed.

Publication types

  • Case Reports
  • English Abstract

MeSH terms

  • Antibodies
  • Cyclosporins / therapeutic use*
  • Drug Therapy, Combination
  • Factor VIII / antagonists & inhibitors*
  • Factor VIII / immunology
  • Female
  • Hemophilia A / drug therapy
  • Hemophilia A / etiology*
  • Hemophilia A / immunology
  • Humans
  • Middle Aged
  • Prednisone / therapeutic use*

Substances

  • Antibodies
  • Cyclosporins
  • Factor VIII
  • Prednisone