Abstract
Two unusual flavonones coupled with styryl units, communins A (1) and B (2), and a new benzonaphthoxanthenone, ohioensin H (3), together with 11 known compounds, were isolated from the moss Polytrichum commune. The structures of 1-3 were assigned by spectroscopic data interpretation. The new compounds were evaluated for cytotoxicity against a small panel of cancer cell lines.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Antineoplastic Agents, Phytogenic / chemistry
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Antineoplastic Agents, Phytogenic / isolation & purification*
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Antineoplastic Agents, Phytogenic / pharmacology
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Bryophyta / chemistry*
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Drug Screening Assays, Antitumor
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Drugs, Chinese Herbal / chemistry
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Drugs, Chinese Herbal / isolation & purification*
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Drugs, Chinese Herbal / pharmacology
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Flavanones / chemistry
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Flavanones / isolation & purification*
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Flavanones / pharmacology
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Heterocyclic Compounds, 4 or More Rings / chemistry
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Heterocyclic Compounds, 4 or More Rings / isolation & purification*
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Heterocyclic Compounds, 4 or More Rings / pharmacology
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Humans
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Molecular Structure
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Nuclear Magnetic Resonance, Biomolecular
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Xanthenes / chemistry
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Xanthenes / isolation & purification*
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Xanthenes / pharmacology
Substances
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Antineoplastic Agents, Phytogenic
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Drugs, Chinese Herbal
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Flavanones
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Heterocyclic Compounds, 4 or More Rings
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Xanthenes
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communin A
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communin B
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ohioensin H