Abstract
In a recent issue of Science, Olive and colleagues document that inhibition of Hedgehog (Hh) signaling in a genetically engineered mouse model of pancreatic cancer can enhance the intratumor concentration of certain anticancer drugs. Could this finding provide us with a new method to attack pancreatic cancer?
MeSH terms
-
Hedgehog Proteins / physiology
-
Humans
-
Incidence
-
Magnetic Resonance Imaging
-
Pain
-
Pancreatic Neoplasms / epidemiology
-
Pancreatic Neoplasms / genetics
-
Pancreatic Neoplasms / mortality
-
Pancreatic Neoplasms / pathology*
-
Pancreatic Neoplasms / physiopathology
-
Perfusion Imaging
-
Survival Analysis
-
United States / epidemiology