Epilepsy and temporal lobe injury after skull base proton beam therapy

Ricardo Horacio Roda; Gary L Gallia; Charles G Eberhart; Jon D Weingart; John Laterra

doi:10.1016/j.jocn.2009.04.003

Epilepsy and temporal lobe injury after skull base proton beam therapy

J Clin Neurosci. 2009 Sep;16(9):1220-1. doi: 10.1016/j.jocn.2009.04.003. Epub 2009 Jul 2.

Authors

Ricardo Horacio Roda¹, Gary L Gallia, Charles G Eberhart, Jon D Weingart, John Laterra

Affiliation

¹ Department of Neurology, Room 5050, Outpatient Center, Johns Hopkins University School of Medicine, 601 North Caroline Street, Baltimore, Maryland 21287, USA. [email protected]

PMID: 19576784
DOI: 10.1016/j.jocn.2009.04.003

Abstract

We present three patients who developed temporal lobe injury and epilepsy after proton beam therapy to the skull base. This particular form of treatment-related toxicity should be considered when treating skull base tumors.

Publication types

Case Reports

MeSH terms

Adult
Brain / pathology
Chondrosarcoma / complications*
Chondrosarcoma / radiotherapy*
Chordoma / complications*
Chordoma / radiotherapy*
Electroencephalography
Epilepsy / etiology*
Female
Humans
Magnetic Resonance Imaging
Male
Meningioma / complications*
Meningioma / radiotherapy*
Middle Aged
Protons
Radiotherapy / adverse effects*
Skull Base Neoplasms / complications*
Skull Base Neoplasms / radiotherapy*
Temporal Lobe / injuries*

Substances

Protons