Effect of body mass index on clinical manifestations in patients with polycystic ovary syndrome

Int J Gynaecol Obstet. 2009 Oct;107(1):54-7. doi: 10.1016/j.ijgo.2009.06.003. Epub 2009 Jul 3.

Abstract

Objective: To determine whether there is a correlation between body mass index (BMI) and blood pressure or clinical features such as hirsutism in women with polycystic ovary syndrome (PCOS).

Method: In this cross-sectional study, 62 women with PCOS were allocated to one of 3 groups according to a BMI range defining normal weight, overweight, or obesity. Blood pressure, waist-to-hip ratio, Ferriman and Gallwey hirsutism score, and presence of acne were recorded for each participant and the means were compared among groups.

Results: The overall mean age was 35.85+/-5.03 years; BMI, 31.91+/-6.40; systolic and diastolic blood pressure, 113.02+/-16.10 mm Hg and 71.79+/-10.04 mm Hg; waist-to-hip ratio, 0.82+/-0.07; and hirsutism score, 3.63+/-4.35. Acne was present in 24 participants. Of these, 8 (33.3%) were overweight and 13 (54.2%) obese. When groups were compared, a progressive and significant increase in systolic and diastolic blood pressure was observed from the normal weight to the obese group.

Conclusion: We observed a significant and progressive correlation between BMI and both blood pressure and clinical features in women with PCOS.

MeSH terms

  • Acne Vulgaris / etiology
  • Adult
  • Blood Pressure*
  • Body Mass Index*
  • Cross-Sectional Studies
  • Female
  • Hirsutism / etiology*
  • Humans
  • Obesity / complications
  • Overweight / complications
  • Polycystic Ovary Syndrome / physiopathology*
  • Waist-Hip Ratio