We show the video of the dissection and resection of a locally advanced jejunal adenocarcinoma, with the involvement of multiple loops, to the base of the mesentery. Complete resection was made possible by careful dissection of the jejunal vessels and superior mesenteric artery at the root of the small-bowel mesentery (see Video, Supplemental Digital Content 1, http://links.lww.com/A1308). The long-term outcome for this patient is good.