Abstract
Triple-reassortant swine influenza A (H1) viruses, containing genes from avian, human, and swine influenza viruses, emerged and became an outbreak among humans worldwide. Over a 1,000 cases were identified within the first month, chiefly in Mexico and the United States. Here, the phylogenetic analysis of haemagglutin (HA), neuraminidase (NA), and matrix protein (MP) was carried out. The analysis showed that the H1 of this reassortant originated from American pigs, while NA and MP were more likely from European pigs. All of the 2009 isolates appear homogeneous and cluster together, although they are distinct from classical human A (H1N1) viruses.
MeSH terms
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Animals
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Antigens, Viral / classification
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Antigens, Viral / genetics*
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Disease Outbreaks*
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Europe
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HN Protein / classification
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HN Protein / genetics
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Hemagglutinin Glycoproteins, Influenza Virus / classification
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Hemagglutinin Glycoproteins, Influenza Virus / genetics
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Humans
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Influenza A Virus, H1N1 Subtype / classification
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Influenza A Virus, H1N1 Subtype / genetics*
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Influenza, Human / epidemiology*
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Influenza, Human / virology*
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Mexico / epidemiology
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Phylogeny
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Reassortant Viruses / classification
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Reassortant Viruses / genetics*
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Swine / virology
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United States / epidemiology
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Viral Matrix Proteins / classification
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Viral Matrix Proteins / genetics
Substances
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Antigens, Viral
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HN Protein
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Hemagglutinin Glycoproteins, Influenza Virus
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M1 protein, Influenza A virus
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Viral Matrix Proteins
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hemagglutinin, human influenza A virus