To bring it back a clinical case of neurofibromatosis of the type 1 (NF1) in service of general surgery complicated of bulky invalidating royal tumours. The 35 year old patient presented on all the body multiples small tumefactions but also of bulky heavy cervico-thoracic royal tumours, invalidating, deteriorating the body and psychic image. A surgical ablation and a cutaneous closing in a time were necessary. The results of this esthetic palliative surgery were very satisfactory. The surgery can be of a great contribution during the evolution of the NF1 especially when the lesions become invalidating.