A new HLA-B*5124 variant, B*512402 allele, identified by sequence-based typing

Tissue Antigens. 2009 Sep;74(3):253-4. doi: 10.1111/j.1399-0039.2009.01307.x. Epub 2009 Jul 13.

Abstract

A novel human leukocyte antigen-B allele, officially named B*512402, was identified in a Korean bone marrow donor. The B*512402 allele shows two nucleotide substitutions compared with B*512401 in exon 3 at codons 135 (GCG --> GCC) and 138 (ACC --> ACG) without any amino acid substitution.

MeSH terms

  • Alleles*
  • Asian People / genetics
  • Base Sequence
  • Bone Marrow Cells / cytology
  • Codon
  • DNA Primers / genetics
  • Exons
  • Genetic Variation*
  • Genotype
  • HLA-B Antigens / chemistry
  • HLA-B Antigens / genetics*
  • Histocompatibility Testing / methods*
  • Humans
  • Korea
  • Molecular Sequence Data
  • Point Mutation
  • Sequence Analysis, DNA
  • Sequence Homology, Nucleic Acid
  • Terminology as Topic
  • Tissue Donors

Substances

  • Codon
  • DNA Primers
  • HLA-B Antigens