Abstract
Parasellar and hypothalamic metastases are uncommon. Their principal clinical manifestation is diabetes insipidus. Associated hypopituitarism is very rare. We report the case of a 54-year-old man with small cell lung cancer and hypopituitarism. A brain magnetic resonance imaging scan revealed a mass in the anterior region of the third ventricle with no clear etiology. The patient began chemotherapy treatment and the mass disappeared, which confirmed the diagnosis of secondary hypopituitarism caused by hypothalamic metastasis from small cell lung cancer.
MeSH terms
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Antineoplastic Combined Chemotherapy Protocols / therapeutic use
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Carcinoma, Small Cell / complications
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Carcinoma, Small Cell / diagnosis
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Carcinoma, Small Cell / drug therapy
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Carcinoma, Small Cell / radiotherapy
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Carcinoma, Small Cell / secondary*
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Combined Modality Therapy
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Cranial Irradiation
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Headache / etiology
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Hormone Replacement Therapy
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Humans
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Hydrocortisone / therapeutic use
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Hypopituitarism / drug therapy
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Hypopituitarism / etiology*
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Hypothalamic Neoplasms / complications
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Hypothalamic Neoplasms / diagnosis
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Hypothalamic Neoplasms / drug therapy
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Hypothalamic Neoplasms / radiotherapy
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Hypothalamic Neoplasms / secondary*
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Lung Neoplasms / complications
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Lung Neoplasms / diagnostic imaging
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Lung Neoplasms / drug therapy
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Lung Neoplasms / pathology*
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Magnetic Resonance Imaging
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Male
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Middle Aged
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Thyroxine / therapeutic use
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Tomography, X-Ray Computed