Partial logistic artificial neural network for competing risks regularized with automatic relevance determination

IEEE Trans Neural Netw. 2009 Sep;20(9):1403-16. doi: 10.1109/TNN.2009.2023654. Epub 2009 Jul 21.

Abstract

Time-to-event analysis is important in a wide range of applications from clinical prognosis to risk modeling for credit scoring and insurance. In risk modeling, it is sometimes required to make a simultaneous assessment of the hazard arising from two or more mutually exclusive factors. This paper applies to an existing neural network model for competing risks (PLANNCR), a Bayesian regularization with the standard approximation of the evidence to implement automatic relevance determination (PLANNCR-ARD). The theoretical framework for the model is described and its application is illustrated with reference to local and distal recurrence of breast cancer, using the data set of Veronesi (1995).

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adolescent
  • Adult
  • Aged
  • Algorithms
  • Automation / methods*
  • Bayes Theorem
  • Breast Neoplasms / diagnosis
  • Computer Simulation
  • Databases, Factual
  • Female
  • Follow-Up Studies
  • Humans
  • Logistic Models*
  • Middle Aged
  • Neoplasm Recurrence, Local / diagnosis
  • Neural Networks, Computer*
  • Nonlinear Dynamics
  • Probability
  • Proportional Hazards Models
  • Risk*
  • Survival Analysis
  • Time Factors
  • Young Adult