Abstract
We assessed the effect of distribution of Haemophilus influenzae type b (Hib) vaccine in the private health care sector on Hib meningitis admissions at a referral hospital in India. The annual mean number of Hib cases was 10.7 before Hib vaccine introduction, falling to 3.8 cases following introduction (P < 0.0001). By contrast, the mean of annual numbers of pneumococcal cases were 3.0 and 4.6, (P = 0.55). Even at relatively low coverage through private sector distribution, Hib vaccine has significant community impact on Hib disease.
MeSH terms
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Haemophilus Vaccines / administration & dosage*
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Haemophilus Vaccines / immunology
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Haemophilus influenzae type b / immunology*
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Humans
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India / epidemiology
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Mass Vaccination
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Meningitis, Haemophilus / epidemiology*
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Meningitis, Haemophilus / immunology*
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Meningitis, Haemophilus / prevention & control
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Meningitis, Pneumococcal / epidemiology
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Meningitis, Pneumococcal / immunology
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Meningitis, Pneumococcal / prevention & control
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Poisson Distribution
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Population Surveillance
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Prospective Studies
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Regression Analysis
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Streptococcus pneumoniae / immunology