Expression of bone morphogenetic protein-15 in human oocyte and cumulus granulosa cells primed with recombinant follicle-stimulating hormone followed by human chorionic gonadotropin

Yongjian Chen; Shuyun Zhao; Jie Qiao; Ping Liu; Ying Lian; Xiaoying Zheng

doi:10.1016/j.fertnstert.2009.05.058

Expression of bone morphogenetic protein-15 in human oocyte and cumulus granulosa cells primed with recombinant follicle-stimulating hormone followed by human chorionic gonadotropin

Fertil Steril. 2009 Dec;92(6):2045-6. doi: 10.1016/j.fertnstert.2009.05.058. Epub 2009 Jul 26.

Authors

Yongjian Chen¹, Shuyun Zhao, Jie Qiao, Ping Liu, Ying Lian, Xiaoying Zheng

Affiliation

¹ Department of Obstetrics and Gynecology, Peking University Third Hospital, Beijing, People's Republic of China.

PMID: 19635612
DOI: 10.1016/j.fertnstert.2009.05.058

Abstract

Bone morphogenetic protein-15 is expressed in oocytes and cumulus granulosa cells. It may play an important role in the hCG-induced oocyte final maturation and corpus luteum (CL) formation.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Adult
Bone Morphogenetic Protein 15 / metabolism*
Cells, Cultured
Chorionic Gonadotropin / pharmacology*
Cumulus Cells / cytology
Cumulus Cells / drug effects
Cumulus Cells / metabolism
Female
Fertilization in Vitro
Follicle Stimulating Hormone / pharmacology*
Granulosa Cells / cytology
Granulosa Cells / drug effects
Granulosa Cells / metabolism*
Humans
In Vitro Techniques
Oocyte Retrieval*
Oocytes / cytology
Oocytes / drug effects
Oocytes / metabolism*
Recombinant Proteins / pharmacology

Substances

BMP15 protein, human
Bone Morphogenetic Protein 15
Chorionic Gonadotropin
Recombinant Proteins
Follicle Stimulating Hormone