Backbone 1H, 13C, and 15N resonance assignments for the 26-kD human de-ubiquitinating enzyme UCH-L3

Biomol NMR Assign. 2007 Jul;1(1):51-3. doi: 10.1007/s12104-007-9012-5. Epub 2007 May 11.

Abstract

To facilitate NMR spectroscopy studies of interactions with various ligands and potential inhibitors, we report the NMR backbone resonance assignments for the 26 kD human enzyme UCH-L3, a member of the ubiquitin C-hydrolase family of ubiquitin-specific cysteine proteases.

MeSH terms

  • Catalytic Domain
  • Cysteine Endopeptidases / chemistry*
  • Cysteine Endopeptidases / genetics
  • Humans
  • Molecular Structure
  • Nuclear Magnetic Resonance, Biomolecular
  • Protein Structure, Secondary
  • Recombinant Proteins / chemistry
  • Recombinant Proteins / genetics
  • Ubiquitin Thiolesterase

Substances

  • Recombinant Proteins
  • UCHL3 protein, human
  • Ubiquitin Thiolesterase
  • Cysteine Endopeptidases