Backbone assignment of human proliferating cell nuclear antigen

Ricardo Sánchez; Daniel Torres; Jesús Prieto; Francisco J Blanco; Ramón Campos-Olivas

doi:10.1007/s12104-007-9068-2

Backbone assignment of human proliferating cell nuclear antigen

Biomol NMR Assign. 2007 Dec;1(2):245-7. doi: 10.1007/s12104-007-9068-2. Epub 2007 Nov 30.

Authors

Ricardo Sánchez¹, Daniel Torres, Jesús Prieto, Francisco J Blanco, Ramón Campos-Olivas

Affiliation

¹ Spanish National Cancer Center, Madrid, Spain.

PMID: 19636876
DOI: 10.1007/s12104-007-9068-2

Abstract

PCNA is an essential factor for DNA replication, repair, chromatin metabolism, and effector of cell-cycle regulatory signals. The assignment of backbone (1)H(N), (13)C(alpha), (13)CO, and (15)N, and sidechain (13)C(beta) resonances of the human PCNA homotrimeric ring ( approximately 90 kDa, 261 residues) is reported here.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Amino Acid Sequence
Carbon Isotopes / chemistry
Humans
Magnetic Resonance Spectroscopy / methods*
Molecular Weight
Nitrogen Isotopes / chemistry
Proliferating Cell Nuclear Antigen / chemistry*
Protein Structure, Tertiary
Protons

Substances

Carbon Isotopes
Nitrogen Isotopes
Proliferating Cell Nuclear Antigen
Protons