Abstract
Most of microbes hijack the cellular machinery to their advantage by interacting with specific target of the host cell. Glycoprotein of rabies virus is a key factor controlling the homeostasis of infected neuronal cells and proteins belonging to the human microtubule associated serine threonine kinase family have been identified as potential cellular partners. As a first step towards its structural study, we have assigned the backbone and side chain nuclei resonances of the PDZ domain (PSD-95, Discs Large, ZO-1) of MAST205 in complex with the C-terminal residues of the glycoprotein of rabies virus. The BMRB accession code is 155972.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Amino Acid Motifs
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Amino Acid Sequence
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Binding Sites
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Carbon Isotopes / chemistry
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Glycoproteins / chemistry*
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Magnetic Resonance Spectroscopy / methods*
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Microtubule-Associated Proteins / chemistry*
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Molecular Sequence Data
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Multiprotein Complexes / chemistry
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Nitrogen Isotopes / chemistry
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Protein Binding
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Protein Serine-Threonine Kinases / chemistry*
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Protein Structure, Tertiary
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Protons
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Rabies virus / chemistry*
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Viral Proteins / chemistry*
Substances
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Carbon Isotopes
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Glycoproteins
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Microtubule-Associated Proteins
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Mtssk protein, mouse
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Multiprotein Complexes
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Nitrogen Isotopes
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Protons
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Viral Proteins
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Protein Serine-Threonine Kinases