Antibacterial coatings on titanium implants

J Biomed Mater Res B Appl Biomater. 2009 Oct;91(1):470-80. doi: 10.1002/jbm.b.31463.

Abstract

Titanium and titanium alloys are key biomedical materials because of their good biocompatibility and mechanical properties. Nevertheless, infection on and around titanium implants still remains a problem which is usually difficult to treat and may lead to eventual implant removal. As a result, preventive measures are necessary to mitigate implant-frelated infection. One important strategy is to render the implant surface antibacterial by impeding the formation of a biofilm. A number of approaches have been proposed for this purpose and they are reviewed in this article.

Publication types

  • Review

MeSH terms

  • Anti-Bacterial Agents / chemistry*
  • Anti-Bacterial Agents / pharmacology
  • Anti-Bacterial Agents / therapeutic use*
  • Bacterial Adhesion / drug effects
  • Biofilms / drug effects
  • Coated Materials, Biocompatible / chemistry*
  • Drug Carriers / chemistry
  • Humans
  • Materials Testing
  • Nitric Oxide / chemistry
  • Nitric Oxide / pharmacology
  • Nitric Oxide / therapeutic use
  • Polymers / chemistry
  • Prostheses and Implants*
  • Prosthesis-Related Infections / prevention & control*
  • Surface Properties
  • Titanium / chemistry*

Substances

  • Anti-Bacterial Agents
  • Coated Materials, Biocompatible
  • Drug Carriers
  • Polymers
  • Nitric Oxide
  • Titanium