Is atherectomy the best first-line therapy for limb salvage in patients with critical limb ischemia?

Vasc Endovascular Surg. 2009 Dec;43(6):542-50. doi: 10.1177/1538574409334825. Epub 2009 Jul 29.

Abstract

Objective: To determine the efficacy of atherectomy for limb salvage compared with open bypass in patients with critical limb ischemia.

Methods: Ninety-nine consecutive bypass and atherectomy procedures performed for critical limb ischemia between January 2003 and October 2006 were reviewed.

Results: A total of 99 cases involving TASC C (n = 43, 44%) and D (n = 56, 56%) lesions were treated with surgical bypass in 59 patients and atherectomy in 33 patients. Bypass and atherectomy achieved similar 1-year primary patency (64% vs 63%; P = .2). However, the 1-year limb salvage rate was greater in the bypass group (87% vs 69%; P = .004). In the tissue loss subgroup, there was a greater limb salvage rate for bypass patients versus atherectomy (79% vs 60%; P = .04).

Conclusions: Patients with critical limb ischemia may do better with open bypass compared with atherectomy as first-line therapy for limb salvage.

Publication types

  • Comparative Study

MeSH terms

  • Aged
  • Atherectomy* / adverse effects
  • Atherectomy* / mortality
  • Blood Vessel Prosthesis Implantation* / adverse effects
  • Blood Vessel Prosthesis Implantation* / mortality
  • Critical Illness
  • Female
  • Humans
  • Ischemia / mortality
  • Ischemia / physiopathology
  • Ischemia / surgery
  • Ischemia / therapy*
  • Kaplan-Meier Estimate
  • Limb Salvage*
  • Lower Extremity / blood supply*
  • Male
  • Middle Aged
  • Proportional Hazards Models
  • Risk Assessment
  • Time Factors
  • Treatment Outcome
  • Vascular Patency
  • Vascular Surgical Procedures* / adverse effects
  • Vascular Surgical Procedures* / mortality
  • Veins / transplantation