Anti-adalimumab antibodies in rheumatoid arthritis patients are associated with interleukin-10 gene polymorphisms

Arthritis Rheum. 2009 Aug;60(8):2541-2. doi: 10.1002/art.24709.
No abstract available

MeSH terms

  • Adalimumab
  • Antibodies / blood
  • Antibodies, Monoclonal / immunology*
  • Antibodies, Monoclonal / therapeutic use
  • Antibodies, Monoclonal, Humanized
  • Antibody Formation / drug effects
  • Antibody Formation / immunology*
  • Antirheumatic Agents / immunology*
  • Antirheumatic Agents / therapeutic use
  • Arthritis, Rheumatoid / drug therapy
  • Arthritis, Rheumatoid / genetics
  • Arthritis, Rheumatoid / immunology*
  • Drug Therapy, Combination
  • Haplotypes / genetics
  • Humans
  • Interleukin-10 / genetics*
  • Methotrexate / immunology
  • Methotrexate / therapeutic use
  • Polymorphism, Single Nucleotide
  • Prospective Studies

Substances

  • Antibodies
  • Antibodies, Monoclonal
  • Antibodies, Monoclonal, Humanized
  • Antirheumatic Agents
  • IL10 protein, human
  • Interleukin-10
  • Adalimumab
  • Methotrexate