[Fournier gangrene (necrotizing fasciitis) in a woman with diabetes mellitus]

Dtsch Med Wochenschr. 2009 Aug;134(33):1625-8. doi: 10.1055/s-0029-1233991. Epub 2009 Jul 31.
[Article in German]

Abstract

History and clinical findings: A 67-year-old woman with insuline-dependent diabetes mellitus and chronic alcohol abuse was admitted with impaired consciousness and fever. Physical examination showed a livid induration of the perineal and vaginal soft tissues with crepitations.

Investigations: Laboratory tests showed greatly elevated infection parameters. Abdominal computed tomography revealed perineal and vaginal subcutaneous gas accumulation extending into the ventral abdominal wall.

Treatment and course: The combination of an obscure infection and subcutaneous genital gas accumulation suggested the diagnosis of Fournier gangrene, a necrotizing fasciitis. In spite of administration of broad-spectrum antibiotics and repeated surgical removal of necrotic tissue the patient died of multiple organ failure.

Conclusion: Successful treatment of Fournier gangrene critically depends on immediate treatment. Administration of broad-spectrum antibiotics and aggressive surgical resection of the necrotic tissue may prevent continuing spreading of the infection. Computed tomography provides an early diagnosis and guides the presurgical evaluation of the subcutaneous spread.

Publication types

  • Case Reports
  • English Abstract

MeSH terms

  • Aged
  • Alcoholism / complications*
  • Anti-Bacterial Agents / therapeutic use
  • Consciousness Disorders
  • Debridement
  • Diabetes Mellitus, Type 2 / complications*
  • Diabetes Mellitus, Type 2 / drug therapy
  • Fasciitis, Necrotizing / diagnosis*
  • Fasciitis, Necrotizing / drug therapy
  • Fasciitis, Necrotizing / surgery
  • Fatal Outcome
  • Female
  • Fever
  • Fournier Gangrene / diagnosis*
  • Fournier Gangrene / drug therapy
  • Fournier Gangrene / surgery
  • Humans
  • Hypoglycemic Agents / therapeutic use
  • Insulin / therapeutic use
  • Obesity / complications
  • Tomography, X-Ray Computed

Substances

  • Anti-Bacterial Agents
  • Hypoglycemic Agents
  • Insulin