Chlorella viruses encode most, if not all, of the machinery to glycosylate their glycoproteins independent of the endoplasmic reticulum and Golgi

Biochim Biophys Acta. 2010 Feb;1800(2):152-9. doi: 10.1016/j.bbagen.2009.07.024. Epub 2009 Aug 3.

Abstract

In contrast to all other viruses that use the host machinery located in the endoplasmic reticulum and Golgi to glycosylate their glycoproteins, the large dsDNA-containing chlorella viruses encode most, if not all, of the components to glycosylate their major capsid proteins. Furthermore, all experimental results indicate that glycosylation occurs independent of the endoplasmic reticulum and Golgi.

Publication types

  • Research Support, N.I.H., Extramural
  • Review

MeSH terms

  • Capsid Proteins / metabolism
  • Chlorella / genetics
  • Chlorella / virology
  • Endoplasmic Reticulum / genetics*
  • Endoplasmic Reticulum / metabolism
  • Glycoproteins / metabolism*
  • Glycosylation
  • Glycosyltransferases / metabolism*
  • Golgi Apparatus / genetics*
  • Golgi Apparatus / metabolism
  • Models, Molecular
  • Phycodnaviridae / enzymology*
  • Phycodnaviridae / genetics

Substances

  • Capsid Proteins
  • Glycoproteins
  • Glycosyltransferases