Successful treatment of childhood cutaneous leishmaniasis with liposomal amphotericin B: report of two cases

J Trop Pediatr. 2010 Apr;56(2):122-4. doi: 10.1093/tropej/fmp073. Epub 2009 Aug 5.

Abstract

Treatment of cutaneous leishmaniasis is sometimes difficult. No single ideal therapy has yet been identified and some of the drugs that are currently used are associated with significant toxicity. We present two cases of cutaneous leishmaniasis in children, one caused by Leishmania infantum and the other by Leishmania braziliensis. Both of them were successfully treated with intravenous liposomal amphotericin B.

Publication types

  • Case Reports

MeSH terms

  • Amphotericin B / administration & dosage*
  • Antiprotozoal Agents / administration & dosage*
  • Child
  • Humans
  • Infant
  • Leishmania braziliensis / drug effects*
  • Leishmania infantum / drug effects*
  • Leishmaniasis, Cutaneous / drug therapy*
  • Leishmaniasis, Cutaneous / parasitology
  • Leishmaniasis, Cutaneous / pathology
  • Liposomes
  • Male
  • Polymerase Chain Reaction
  • Treatment Outcome

Substances

  • Antiprotozoal Agents
  • Liposomes
  • Amphotericin B