Unexpectedly high AUC levels in a child who received intravenous busulfan before stem cell transplantation

Bone Marrow Transplant. 2010 Mar;45(3):602-4. doi: 10.1038/bmt.2009.195. Epub 2009 Aug 17.
No abstract available

Publication types

  • Case Reports
  • Letter
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Area Under Curve
  • Busulfan / administration & dosage
  • Busulfan / adverse effects*
  • Busulfan / pharmacokinetics*
  • Cerebellar Neoplasms / therapy
  • Child
  • Drug Monitoring
  • Fatal Outcome
  • Glutathione Transferase / genetics
  • Glutathione Transferase / metabolism
  • Humans
  • Injections, Intravenous
  • Lung / drug effects
  • Lung / pathology
  • Male
  • Medulloblastoma / therapy
  • Myeloablative Agonists / administration & dosage
  • Myeloablative Agonists / adverse effects*
  • Myeloablative Agonists / pharmacokinetics*
  • Peripheral Blood Stem Cell Transplantation*
  • Transplantation Conditioning / adverse effects*
  • Transplantation, Autologous

Substances

  • Myeloablative Agonists
  • GSTA1 protein, human
  • Glutathione Transferase
  • Busulfan