Preliminary report: isolation of Ebola virus from monkeys imported to USA

Lancet. 1990 Mar 3;335(8688):502-5. doi: 10.1016/0140-6736(90)90737-p.

Abstract

An epizootic caused by an Ebola-related filovirus and by simian haemorrhagic fever virus began among cynomolgus monkeys in a US quarantine facility after introduction of monkeys from the Philippines. This incident, the first in which a filovirus has been isolated from non-human primates without deliberate infection, raises the possibility that cynomolgus monkeys could be a reservoir of Ebola virus infection.

MeSH terms

  • Animals
  • Antibodies, Monoclonal
  • Antigens, Viral / analysis
  • Commerce*
  • Disease Outbreaks
  • Ebolavirus / immunology
  • Ebolavirus / isolation & purification*
  • Enzyme-Linked Immunosorbent Assay
  • Fluorescent Antibody Technique
  • Hemorrhagic Fevers, Viral / diagnosis
  • Hemorrhagic Fevers, Viral / epidemiology
  • Hemorrhagic Fevers, Viral / microbiology
  • Hemorrhagic Fevers, Viral / veterinary*
  • Immunohistochemistry
  • Liver / microbiology
  • Macaca fascicularis
  • Microscopy, Electron
  • Monkey Diseases / diagnosis
  • Monkey Diseases / epidemiology
  • Monkey Diseases / microbiology*
  • Philippines
  • Rhabdoviridae / isolation & purification*
  • Spleen / microbiology
  • United States / epidemiology

Substances

  • Antibodies, Monoclonal
  • Antigens, Viral