Abstract
We retrospectively assessed the renal toxicity associated with the use of intravenous colistin. Fifty-four patients with multidrug-resistant Acinetobacter infections were included. At the end of therapy 6/54 patients (11%) suffered renal impairment. Renal impairment associated with the use of colistin is less frequent than initially reported.
MeSH terms
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Acinetobacter Infections / drug therapy
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Adult
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Anti-Bacterial Agents / administration & dosage
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Anti-Bacterial Agents / adverse effects*
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Anti-Bacterial Agents / pharmacology
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Colistin / administration & dosage
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Colistin / adverse effects*
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Colistin / pharmacology
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Creatinine / blood
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Humans
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Injections, Intravenous
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Kidney Diseases / blood
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Kidney Diseases / chemically induced*
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Kidney Function Tests
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Microbial Sensitivity Tests
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Retrospective Studies
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Statistics, Nonparametric
Substances
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Anti-Bacterial Agents
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Creatinine
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Colistin